HomeOrthopedicsOrthopedic NewsIn elderly women, any initial bone fracture increases their chance of further...

In elderly women, any initial bone fracture increases their chance of further fractures

Bone fracture

Postmenopausal women with an initial bone fracture, even in the arm or wrist, have a 3 to 6 times higher threat for subsequent bone fractures, according to a study published online May 5 in EClinicalMedicine.

Carolyn J. Crandall, M.D., from the University of California, Los Angeles, and colleagues assessed subsequent fractures after initial fracture among participants in the Women’s Health Initiative (1993 to 2018). The analysis included 47,458 participants with incident fracture (baseline age, 50 to 79 years) with a mean of 15.4 years of follow-up.


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The researchers found that the chance for every kind of subsequent fracture was increased after each initial fracture. Following an incident lower arm/wrist fracture, there was a big affiliation with elevated risks for subsequent fractures on the upper arm/shoulder, upper leg, knee, lower leg/ankle, hip/pelvis, and backbone (adjusted hazard ratios [aHRs] vary, 2.63 to five.68). After an initial lower arm or wrist fracture, the chance for hip fracture increased (aHR, 4.80). Similar outcomes were observed following an initial higher arm or shoulder fracture (aHR, 5.06), initial higher leg fracture (aHR, 5.11), initial knee fracture (aHR, 5.03), initial decrease leg/ankle fracture (aHR, 4.10), and initial backbone fracture (aHR, 6.69). All age teams confirmed vital associations, with subsequent fracture risk more pronounced among non-Hispanic Black, Hispanic/Latina, and Asian/Pacific Islander women versus non-Hispanic White women.

“Women who experience any of those fractures must be targeted for interventions to prevent subsequent fractures,” the authors write.

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